BAI1 (hydrochloride)
BAI1 hydrochloride is a selective apoptosis factor BAX allosteric inhibitors. BAI1 hydrochloride binds BAX and allosterically inhibits its activation. BAI1 hydrochloride has the potential to be used in the study of BAX dependent cell death-mediated diseases[1].
Product Specifications
CAS Number
[329349-20-4]
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Apoptosis; Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bai1-hydrochloride.html
Purity
99.82
Solubility
DMSO : 5 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
BrC1=CC=C2C(C3=C(N2CC(CN4CCNCC4)O)C=CC(Br)=C3)=C1.Cl.Cl
Molecular Formula
C19H23Br2Cl2N3O
Molecular Weight
540.12
Precautions
H315, H319, H320
References & Citations
[1]Garner TP, et al. Small-molecule allosteric inhibitors of BAX. Nat Chem Biol. 2019 Apr;15 (4) :322-330.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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