(S)-WAY 100135 (dihydrochloride)
Product Specifications
UNSPSC Description
(S)-WAY 100135 dihydrochloride is a highly selective and potent antagonist of 5-HT 1A (IC50=33.9 nM). (S)-WAY 100135 dihydrochloride has anxiolytic activity in animal models[1].
Target Antigen
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/s-way-100135-dihydrochloride.html
Solubility
10 mM in DMSO
Smiles
COC1=C(N2CCN(CC2)C[C@H](C3=CC=CC=C3)C(NC(C)(C)C)=O)C=CC=C1.Cl.Cl
Molecular Weight
468.46
References & Citations
[1]Cliffe IA, et al. (S)-N-tert-butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamide [(S)-WAY-100135]: a selective antagonist at presynaptic and postsynaptic 5-HT1A receptors. J Med Chem. 1993 May 14;36(10):1509-10.
Shipping Conditions
Room temperature
Storage Conditions
Store at room temperature, keep dry and cool
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-110001/S-WAY-100135-dihydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-110001/
Clinical Information
No Development Reported
CAS Number
149007-54-5
Curated Selection
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