Posenacaftor
Posenacaftor (PTI-801) is a cystic fibrosis transmembrane regulator (CFTR) protein modulator that corrects the folding and trafficking of CFTR protein. Posenacaftor is used for the research of cystic fibrosis (CF) [1].
Product Specifications
CAS Number
[2095064-05-2]
Product Name Alternative
PTI-801
UNSPSC
12352005
Target
CFTR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/posenacaftor.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(C2=C(C)C3=CC=CC=C3O2)=NC4=C(C)C=CC(O[C@@H](C5CCOCC5)C)=C14)O
Molecular Formula
C27H27NO5
Molecular Weight
445.51
References & Citations
[1]Benjamin Kopp, et al. Compositions et procédés pour améliorer la fonction cftr dans des cellules affectées par la fibrose kystique. Patent WO2019156946.|[2]Posenacaftor (PTI-801)
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
586840-01 20 µg
Basic Leucine Zipper and W2 Domain-containing Protein 2, Active, Recombinant, Human, GST-Tag, aa1-419 (BZW2)
Ask
View Details 
586840-02 100 µg
Basic Leucine Zipper and W2 Domain-containing Protein 2, Active, Recombinant, Human, GST-Tag, aa1-419 (BZW2)
Ask
View Details 