Bomedemstat
Bomedemstat (IMG-7289) is an orally active and irreversible lysine-specific demethylase 1 (LSD1) inhibitor. Bomedemstat can increase H3K4 and H3K9 methylation, and then alter gene expression. Bomedemstat shows anti-cancer activities, inhibits cancer cell proliferation and induces apoptosis[1][2].
Product Specifications
CAS Number
[1990504-34-1]
Product Name Alternative
IMG-7289
UNSPSC
12352005
Target
Apoptosis; Histone Demethylase
Type
Reference compound
Related Pathways
Apoptosis; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bomedemstat.html
Purity
99.55
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(N1CCN(CC1)C)[C@@H](NC(C2=CC=C(N3C=CN=N3)C=C2)=O)CCCN[C@H]4[C@@](C5=CC=C(C=C5)F)([H])C4
Molecular Formula
C28H34FN7O2
Molecular Weight
519.61
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-109169/Bomedemstat-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-109169/Bomedemstat-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
KDM1/LSD1
Available Sizes
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