Arfolitixorin (sulfate)
Arfolitixorin sulfate is a potent 5-Fluorouracil (5-FU) moderator. Arfolitixorin sulfate is an immediately active form of Folate, [6R]-5,10-methylenetetrahydrofolate ([6R]-MTHF) . Arfolitixorin sulfate is potent for the research of metastatic colorectal cancer[1].
Product Specifications
CAS Number
149930-93-8
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/arfolitixorin-sulfate.html
Solubility
10 mM in DMSO
Smiles
O=C(NC(N)=N1)C2=C1NC[C@@]3([H])N2CN(C4=CC=C(C(N[C@H](C(O)=O)CCC(O)=O)=O)C=C4)C3.O=S(O)(O)=O
Molecular Formula
C20H25N7O10S
Molecular Weight
555.52
References & Citations
[1]Carlsson G, et al. A phase I/II study of arfolitixorin and 5-fluorouracil in combination with oxaliplatin (plus or minus bevacizumab) or irinotecan in metastatic colorectal cancer. ESMO Open. 2022 Oct;7 (5) :100589.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC040352-500 1x 500 µL
CD31 / PECAM-1 (158-2B3), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC881429-500 1x 500 µL
E-Cadherin / CD324 (Intercellular Junction Marker) (4A2), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC401922-500 1x 500 µL
TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1922), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC681634-100 1x 100 µL
P53 Tumor Suppressor Protein (PAb240), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC880673-500 1x 500 µL
Cyclin A2 (E67), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details