Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Rosiptor (acetate)

Rosiptor (AQX-1125) acetate is a selective and orally active phosphatase SHIP1 activator with anti-inflammatory effects. Rosiptor acetate (AQX-1125) inhibits Akt phosphorylation, inflammatory mediator production and leukocyte chemotaxis in vitro[1][2].

Product Specifications

CAS Number

[782487-29-0]

Product Name Alternative

AQX-1125 (acetate)

UNSPSC

12352211

Hazard Statement

H302-H315-H319-H335

Target

Phosphatase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/rosiptor-acetate.html

Solubility

10 mM in DMSO

Smiles

C[C@@]([C@H]1CO)(CC[C@H](O)C1)[C@](CC[C@@]2(C)[C@@]3([H])CCC2=C)([H])[C@H]3CN.CC(O)=O

Molecular Formula

C22H39NO4

Molecular Weight

381.55

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Stenton GR, et al. Characterization of AQX-1125, a small-molecule SHIP1 activator: Part 1. Effects on inflammatory cell activation and chemotaxis in vitro and pharmacokinetic characterization in vivo. Br J Pharmacol. 2013 Mar;168 (6) :1506-18.|[2]Cross J, et al. AQX-1125, small molecule SHIP1 activator inhibits NSC-125066-induced pulmonary fibrosis. Br J Pharmacol. 2017 Sep;174 (18) :3045-3057.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-109011A/Rosiptor-acetate-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-109011A/

Scientific Category

Reference compound1

Clinical Information

Phase 3

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Noxp20 (m) -PR
sc-150039-PR 10 µM - 20 µL

Noxp20 (m) -PR

Ask
View Details
Olfr1310 (NM_146449) Mouse Tagged ORF Clone Lentiviral Particle
MR226755L4V 200 µL

Olfr1310 (NM_146449) Mouse Tagged ORF Clone Lentiviral Particle

Ask
View Details
Sox-21 (2G10)
sc-293461 100 µg/mL

Sox-21 (2G10)

Ask
View Details