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Palonidipine

Palonidipine is a calcium antagonist which is potential for the therapy of angina-pectoris and hypertension[1][2][3].

Product Specifications

CAS Number

96515-73-0

UNSPSC

12352005

Target

Calcium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/palonidipine.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=C(C)NC(C)=C(C(OC)=O)C1C2=CC([N+]([O-])=O)=CC=C2F)OCC(C)(C)CN(C)CC3=CC=CC=C3

Molecular Formula

C29H34FN3O6

Molecular Weight

539.60

References & Citations

[1]Okamiya Y, et al. [Effect of palonidipine hydrochloride (TC-81), a novel calcium antagonist, on the canine coronary artery]. Nihon Yakurigaku Zasshi. 1993 Jul;102 (1) :23-33.|[2]Kishimoto T, et al. [Effect of palonidipine hydrochloride (TC-81), a new dihydropyridine derivative, on various myocardial ischemic models]. Nihon Yakurigaku Zasshi. 1993 Aug;102 (2) :85-100.|[3]K. Sunakawa, et al. Effects of palonidipine hydrochloride on respiratory and cardiovascular systems. January 1993

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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