VUF 8430
Product Specifications
UNSPSC Description
VUF 8430 is a potent and selective histamine H4 receptor agonist with a Ki of 31.6 nM and an EC50 of 50 nM[1].
Target Antigen
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
neurological disease
Assay Protocol
https://www.medchemexpress.com/vuf-8430.html
Solubility
10 mM in DMSO
Smiles
NC(SCCNC(N)=N)=N
Molecular Weight
161.23
References & Citations
[1]Lim HD, et al. Discovery of S-(2-guanidylethyl)-isothiourea (VUF 8430) as a potent nonimidazole histamine H4 receptor agonist. J Med Chem. 2006 Nov 16;49(23):6650-1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-108977/VUF-8430-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-108977/
Clinical Information
No Development Reported
CAS Number
98021-17-1
Curated Selection
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