Raclopride (tartrate)
Raclopride tartrate is a selective dopamine D2/D3 receptor antagonist with potential antipsychotic effects. Raclopride tartrate binds to D2 and D3 receptors with Kis of 1.8 nM and 3.5 nM, respectively[1][2].
Product Specifications
CAS Number
98185-20-7
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/raclopride-tartrate.html
Solubility
10 mM in DMSO
Smiles
O=C(NC[C@H]1N(CC)CCC1)C2=C(OC)C(Cl)=CC(Cl)=C2O.O=C(O)[C@H](O)[C@@H](O)C(O)=O
Molecular Formula
C19H26Cl2N2O9
Molecular Weight
497.32
References & Citations
[1]Seeman P, et al. Dopamine receptor pharmacology. Trends Pharmacol Sci. 1994;15 (7) :264-270. |[2]Aguilar MA, et al. Behavioral profile of raclopride in agonistic encounters between male mice. Pharmacol Biochem Behav. 1994;47 (3) :753-756.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 4
Isoform
D1 Receptor; D2 Receptor; D3 Receptor; D4 Receptor
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