SQ 29548

SQ 29548 is a selective thromboxane-prostanoid (TP) receptor antagonist[1][2].

Product Specifications

CAS Number

[98672-91-4]

UNSPSC

12352005

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/sq-29548.html

Purity

99.9

Solubility

DMSO : 5 mg/mL (ultrasonic; warming)

Smiles

O=C(NC1=CC=CC=C1)NNC[C@H]2[C@H]([C@H]3O[C@@H]2CC3)C/C=C\CCCC(O)=O

Molecular Formula

C21H29N3O4

Molecular Weight

387.47

References & Citations

[1]Isabella Lawandy, et al. Increased coronary arteriolar contraction to serotonin in juvenile pigs with metabolic syndrome. Mol Cell Biochem. 2019 Nov;461 (1-2) :57-64.|[2]A Hedberg, et al. Characterization of [5, 6-3H] SQ 29,548 as a high affinity radioligand, binding to thromboxane A2/prostaglandin H2-receptors in human platelets. J Pharmacol Exp Ther. 1988 Jun;245 (3) :786-92.