Hyaluronidase (human recombinant)

Hyaluronidase (human recombinant) (Vorhyaluronidase alfa; rHuPH 20) is an enzyme that catalyzes the degradation of hyaluronic acid. Hyaluronidase (human recombinant) is used to improve the absorption and dispersal of parenteral fluids, medications, and contrast media[1].

Product Specifications

CAS Number

[37326-33-3]

Product Name Alternative

Vorhyaluronidase alfa; rHuPH 20

UNSPSC

12352204

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents; Glycosidase

Type

Enzyme

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

Cancer-programmed cell death

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/hyaluronidase-human-recombinant.html

Purity

Solubility

10 mM in DMSO

Smiles

[Hyaluronidase(humanrecombinant)]

Precautions

H302, H315, H319, H335

References & Citations

[1]E J Menzel, et al. Hyaluronidase and its substrate hyaluronan: biochemistry, biological activities and therapeutic uses. Cancer Lett. 1998 Sep 11;131 (1) :3-11.|[2]Evison M, et al. Human recombinant hyaluronidase (Cumulase) improves intracytoplasmic sperm injection survival and fertilization rates. Reprod Biomed Online. 2009 Jun;18 (6) :811-4. |[3]Gao X, et al. Mechanistic Modeling of the Effect of Recombinant Human Hyaluronidase (rHuPH20) on Subcutaneous Delivery of Cetuximab in Rats. Pharm Res. 2022 Aug;39 (8) :1867-1880.