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Iduronate sulfatase

Iduronate sulfatase (Iduronate sulfate sulfatase) is an exo-sulfatase that hydrolyzes the C2-sulfate ester bond from nonreducing terminal α-L-iduronic acid residues in HS[1][2].

Product Specifications

CAS Number

50936-59-9

Product Name Alternative

Iduronate sulfate sulfatase

UNSPSC

12352204

Target

Endogenous Metabolite

Type

Enzyme

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/iduronate-sulfatase.html

Solubility

10 mM in DMSO

Smiles

[Iduronatesulfatase]

References & Citations

[1]Arguello A, et al. Iduronate-2-sulfatase transport vehicle rescues behavioral and skeletal phenotypes in a mouse model of Hunter syndrome. JCI Insight. 2021 Oct 8;6 (19) :e145445.|[2]Freeman C, et al. Lysosomal degradation of heparin and heparan sulphate. Adv Exp Med Biol. 1992;313:121-34.

Shipping Conditions

Room temperature

Scientific Category

Enzyme

Clinical Information

Launched

Frequently Asked Questions

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