Iduronate sulfatase
Iduronate sulfatase (Iduronate sulfate sulfatase) is an exo-sulfatase that hydrolyzes the C2-sulfate ester bond from nonreducing terminal α-L-iduronic acid residues in HS[1][2].
Product Specifications
CAS Number
50936-59-9
Product Name Alternative
Iduronate sulfate sulfatase
UNSPSC
12352204
Target
Endogenous Metabolite
Type
Enzyme
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/iduronate-sulfatase.html
Solubility
10 mM in DMSO
Smiles
[Iduronatesulfatase]
References & Citations
[1]Arguello A, et al. Iduronate-2-sulfatase transport vehicle rescues behavioral and skeletal phenotypes in a mouse model of Hunter syndrome. JCI Insight. 2021 Oct 8;6 (19) :e145445.|[2]Freeman C, et al. Lysosomal degradation of heparin and heparan sulphate. Adv Exp Med Biol. 1992;313:121-34.
Shipping Conditions
Room temperature
Scientific Category
Enzyme
Clinical Information
Launched
Frequently Asked Questions
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