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GPR120 Agonist 1

GPR120 Agonist 1 is a potent and selective GPR120 agonist, and possesses promising antidiabetic effect and good safety profile to be a development candidate[1].

Product Specifications

CAS Number

1628448-77-0

UNSPSC

12352005

Target

Free Fatty Acid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/gpr120-agonist-1.html

Solubility

10 mM in DMSO

Smiles

ClC1=CC(F)=C(C2=NSC(C(F)(F)F)=C2COC3=C(F)C=C(CCC(O)=O)C=C3F)C=C1

Molecular Formula

C20H12ClF6NO3S

Molecular Weight

495.82

References & Citations

[1]Zhang X, et al. Discovery of an Isothiazole-Based Phenylpropanoic Acid GPR120 Agonist as a Development Candidate for Type 2 Diabetes. ACS Med Chem Lett. 2017 Jul 27;8 (9) :947-952.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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