GPR120 Agonist 1
GPR120 Agonist 1 is a potent and selective GPR120 agonist, and possesses promising antidiabetic effect and good safety profile to be a development candidate[1].
Product Specifications
CAS Number
[1628448-77-0]
UNSPSC
12352005
Target
Free Fatty Acid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/gpr120-agonist-1.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC(F)=C(C2=NSC(C(F)(F)F)=C2COC3=C(F)C=C(CCC(O)=O)C=C3F)C=C1
Molecular Formula
C20H12ClF6NO3S
Molecular Weight
495.82
References & Citations
[1]Zhang X, et al. Discovery of an Isothiazole-Based Phenylpropanoic Acid GPR120 Agonist as a Development Candidate for Type 2 Diabetes. ACS Med Chem Lett. 2017 Jul 27;8 (9) :947-952.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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