Enterodiol
Enterodiol is transformed by human intestinal bacteria from lignans contained in various whole-grain cereals, nuts, legumes, flaxseed, and vegetables. Enterodiol has an apoptotic effect in colorectal cancer (CRC) cells. Anti-cancer activities[1][2].
Product Specifications
CAS Number
80226-00-2
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
Apoptosis; Endogenous Metabolite
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Enterodiol.html
Solubility
10 mM in DMSO
Smiles
OC[C@H](CC1=CC=CC(O)=C1)[C@@H](CC2=CC=CC(O)=C2)CO
Molecular Formula
C18H22O4
Molecular Weight
302.36
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
References & Citations
[1]Shin MK, et al. Apoptotic effect of enterodiol, the final metabolite of edible lignans, in colorectal cancer cells. J Sci Food Agric. 2019;99 (5) :2411-2419.|[2]Liu H, et al. Enterolactone has stronger effects than enterodiol on ovarian cancer. J Ovarian Res. 2017;10 (1) :49. Published 2017 Jul 24.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
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