Enterodiol

Enterodiol is transformed by human intestinal bacteria from lignans contained in various whole-grain cereals, nuts, legumes, flaxseed, and vegetables. Enterodiol has an apoptotic effect in colorectal cancer (CRC) cells. Anti-cancer activities[1][2].

Product Specifications

CAS Number

[80226-00-2]

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

Apoptosis; Endogenous Metabolite

Type

Reference compound

Related Pathways

Apoptosis; Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Enterodiol.html

Solubility

10 mM in DMSO

Smiles

OC[C@H](CC1=CC=CC(O)=C1)[C@@H](CC2=CC=CC(O)=C2)CO

Molecular Formula

C18H22O4

Molecular Weight

302.36

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

References & Citations

[1]Shin MK, et al. Apoptotic effect of enterodiol, the final metabolite of edible lignans, in colorectal cancer cells. J Sci Food Agric. 2019;99 (5) :2411-2419.|[2]Liu H, et al. Enterolactone has stronger effects than enterodiol on ovarian cancer. J Ovarian Res. 2017;10 (1) :49. Published 2017 Jul 24.