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DMPQ (dihydrochloride)

DMPQ dihydrochloride is a potent and selective inhibitor of human platelet-derived growth factor receptor β (PDGFRβ) with an IC50 of 80 nM[1].

Product Specifications

CAS Number

1123491-15-5

UNSPSC

12352005

Hazard Statement

H302

Target

PDGFR

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dmpq-dihydrochloride.html

Purity

99.10

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

COC1=CC(OC)=C2C=C(C3=CC=NC=C3)C=NC2=C1.[H]Cl.[H]Cl

Molecular Formula

C16H16Cl2N2O2

Molecular Weight

339.22

Precautions

H302

References & Citations

[1]Dolle RE, et al. 5,7-Dimethoxy-3- (4-pyridinyl) quinoline is a potent and selective inhibitor of human vascular beta-type platelet-derived growth factor receptor tyrosine kinase. J Med Chem. 1994 Aug 19;37 (17) :2627-9.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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