DMPQ (dihydrochloride)
DMPQ dihydrochloride is a potent and selective inhibitor of human platelet-derived growth factor receptor β (PDGFRβ) with an IC50 of 80 nM[1].
Product Specifications
CAS Number
[1123491-15-5]
UNSPSC
12352005
Hazard Statement
H302
Target
PDGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/dmpq-dihydrochloride.html
Purity
99.10
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
COC1=CC(OC)=C2C=C(C3=CC=NC=C3)C=NC2=C1.[H]Cl.[H]Cl
Molecular Formula
C16H16Cl2N2O2
Molecular Weight
339.22
Precautions
H302
References & Citations
[1]Dolle RE, et al. 5,7-Dimethoxy-3- (4-pyridinyl) quinoline is a potent and selective inhibitor of human vascular beta-type platelet-derived growth factor receptor tyrosine kinase. J Med Chem. 1994 Aug 19;37 (17) :2627-9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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