Atizoram
Atizoram (CP-80,633), a cyclic nucleotide phosphodiesterase (PDE4) inhibitor, elevates plasma cyclic AMP levels and decreases tumor necrosis factor-α (TNFα) production in mice[1].
Product Specifications
CAS Number
135637-46-6
Product Name Alternative
CP-80,633
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/atizoram.html
Purity
96.3
Solubility
DMF : 3 mg/mL (ultrasonic; warming)
Smiles
COC(C=CC(C1CNC(NC1)=O)=C2)=C2O[C@@H]3[C@@H]4C[C@@H](CC4)C3
Molecular Formula
C18H24N2O3
Molecular Weight
316.39
References & Citations
[1]J B Cheng, et al. The phosphodiesterase type 4 (PDE4) inhibitor CP-80,633 elevates plasma cyclic AMP levels and decreases tumor necrosis factor-alpha (TNFalpha) production in mice: effect of adrenalectomy. J Pharmacol Exp Ther. 1997 Feb;280 (2) :621-6.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE4
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
orb2703961-01 1 mg
SAR428926 Biosimilar (LAMP1 / CD107a Reference Antibody)
Sign In for Pricing
View Details orb2703961-02 5 mg
SAR428926 Biosimilar (LAMP1 / CD107a Reference Antibody)
Sign In for Pricing
View Details orb2703961-03 100 mg
SAR428926 Biosimilar (LAMP1 / CD107a Reference Antibody)
Sign In for Pricing
View Details