YM-26734
YM-26734 is a competitive inhibitor of secretory phospholipase A2 (PLA2) that exhibits a broad inhibitory profile to several PLA2s[1].
Product Specifications
CAS Number
144337-18-8
UNSPSC
12352005
Target
Phospholipase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ym-26734.html
Purity
99.7
Solubility
10 mM in DMSO
Smiles
OC1=C(C(CCCCCCCCCCC)=O)C(O)=C(C(CCCCCCCCCCC)=O)C(O)=C1C2CC(C3=CC=C(O)C=C3)OC4=CC(O)=CC=C24
Molecular Formula
C45H62O8
Molecular Weight
730.97
References & Citations
[1]Miyake A, et al. Suppression of inflammatory responses to 12-O-tetradecanoyl-phorbol-13-acetate and carrageenin by YM-26734, a selective inhibitor of extracellular group II phospholipase A2. Br J Pharmacol. 1993 Sep;110 (1) :447-53.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Phospholipase A
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