WAY 316606 (hydrochloride)
WAY 316606 hydrochloride is an inhibitor of the secreted protein sFRP-1, an endogenous antagonist of the secreted glycoprotein Wnt. The affinity of WAY-316606 for sFRP-1 is determined using the FP binding assay with IC50 of 0.5 μM[1].
Product Specifications
CAS Number
1781835-02-6
UNSPSC
12352005
Target
SFRP-1; Wnt
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/way-316606-hydrochloride.html
Purity
98.04
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=S(C1=CC=C(C(S(NC2CCNCC2)(=O)=O)=C1)C(F)(F)F)(C3=CC=CC=C3)=O.Cl
Molecular Formula
C18H20ClF3N2O4S2
Molecular Weight
484.94
References & Citations
[1]Moore WJ, et al. Modulation of Wnt signaling through inhibition of secreted frizzled-related protein I (sFRP-1) with N-substituted piperidinyl diphenylsulfonyl sulfonamides. J Med Chem. 2009 Jan 8;52 (1) :105-16.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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