WAY 316606 (hydrochloride)

WAY 316606 hydrochloride is an inhibitor of the secreted protein sFRP-1, an endogenous antagonist of the secreted glycoprotein Wnt. The affinity of WAY-316606 for sFRP-1 is determined using the FP binding assay with IC50 of 0.5 μM[1].

Product Specifications

CAS Number

[1781835-02-6]

UNSPSC

12352005

Target

SFRP-1; Wnt

Type

Reference compound

Related Pathways

Stem Cell/Wnt

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/way-316606-hydrochloride.html

Purity

98.04

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=S(C1=CC=C(C(S(NC2CCNCC2)(=O)=O)=C1)C(F)(F)F)(C3=CC=CC=C3)=O.Cl

Molecular Formula

C18H20ClF3N2O4S2

Molecular Weight

484.94

References & Citations

[1]Moore WJ, et al. Modulation of Wnt signaling through inhibition of secreted frizzled-related protein I (sFRP-1) with N-substituted piperidinyl diphenylsulfonyl sulfonamides. J Med Chem. 2009 Jan 8;52 (1) :105-16.