S26948
S26948 is a specific peroxisome proliferator-activated receptor γ (PPARγ) modulator (EC50=8.83 nM) with potent antidiabetes and antiatherogenic effects. S26948 is a specific high-affinity agonist for PPARγ[1].
Product Specifications
CAS Number
353280-43-0
UNSPSC
12352005
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/s26948.html
Solubility
10 mM in DMSO
Smiles
O=C(OC)C(CC1=CC=C(OCCN2C(SC3=CC(C(C4=CC=CC=C4)=O)=CC=C23)=O)C=C1)C(OC)=O
Molecular Formula
C28H25NO7S
Molecular Weight
519.57
References & Citations
[1]Maria Carmen Carmona, et al. S 26948: a new specific peroxisome proliferator activated receptor gamma modulator with potent antidiabetes and antiatherogenic effects. Diabetes. 2007 Nov;56 (11) :2797-808.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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