NTZDpa

NTZDpa is an antibiotic. nTZDpa is a PPARG partial agonist. nTZDpa has antibacterial activity. nTZDpa is effective against growing and persistent Staphylococcus aureus by lipid bilayer disruption[1].

Product Specifications

CAS Number

118414-59-8

UNSPSC

12352005

Hazard Statement

H301

Target

Antibiotic; Bacterial; PPAR

Type

Reference compound

Related Pathways

Anti-infection; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ntzdpa.html

Purity

98.53

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C(N1CC2=CC=C(Cl)C=C2)=C(SC3=CC=CC=C3)C4=C1C=CC(Cl)=C4)O

Molecular Formula

C22H15Cl2NO2S

Molecular Weight

428.33

Precautions

H301

References & Citations

[1]Kim W, et al. Discovery and Optimization of nTZDpa as an Antibiotic Effective Against Bacterial Persisters. ACS Infect Dis. 2018 Nov 9;4 (11) :1540-1545.