NTZDpa
NTZDpa is an antibiotic. nTZDpa is a PPARG partial agonist. nTZDpa has antibacterial activity. nTZDpa is effective against growing and persistent Staphylococcus aureus by lipid bilayer disruption[1].
Product Specifications
CAS Number
[118414-59-8]
UNSPSC
12352005
Hazard Statement
H301
Target
Antibiotic; Bacterial; PPAR
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ntzdpa.html
Purity
98.53
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C(N1CC2=CC=C(Cl)C=C2)=C(SC3=CC=CC=C3)C4=C1C=CC(Cl)=C4)O
Molecular Formula
C22H15Cl2NO2S
Molecular Weight
428.33
Precautions
H301
References & Citations
[1]Kim W, et al. Discovery and Optimization of nTZDpa as an Antibiotic Effective Against Bacterial Persisters. ACS Infect Dis. 2018 Nov 9;4 (11) :1540-1545.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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