L 655240

L 655240 is thromboxane antagonist. L 655240 attenuates early ischemia- and reperfusion-induced arrhythmias in a canine model of coronary artery occlusion. L 655240 also involves in cancer and autoimmune disorders[1].

Product Specifications

CAS Number

[103253-15-2]

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/l-655240.html

Solubility

10 mM in DMSO

Smiles

O=C(O)C(C)(C)CC(N1CC2=CC=C(Cl)C=C2)=C(C)C3=C1C=CC(F)=C3

Molecular Formula

C21H21ClFNO2

Molecular Weight

373.85

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

References & Citations

[1]Wainwright CL, et al. The effects of L655,240, a selective thromboxane and prostaglandin endoperoxide antagonist, on ischemia- and reperfusion-induced cardiac arrhythmias. J Cardiovasc Pharmacol. 1988 Sep;12 (3) :264-71.