SC-51322

SC-51322 is a potent and selective antagonist of prostaglandin E2 (PGE2) receptor (EP 1), with a pA2 of 8.1. SC-51322 has the pain-relieving effect[1].

Product Specifications

CAS Number

[146032-79-3]

UNSPSC

12352005

Hazard Statement

H301

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/sc-51322.html

Purity

98.93

Solubility

DMSO : 20 mg/mL (ultrasonic)

Smiles

O=C(N1C2=CC(Cl)=CC=C2OC3=CC=CC=C3C1)NNC(CCSCC4=CC=CO4)=O

Molecular Formula

C22H20ClN3O4S

Molecular Weight

457.93

Precautions

H301

References & Citations

[1]Hallinan EA, et, al. 8-chlorodibenz[b, f][1,4]oxazepine-10 (11H) -carboxylic acid,2-[3-[2- (furanylmethyl) thio]-1-oxopropyl]hydrazide (SC-51322) : A potent PGE2 antagonist and analgesic. Bioorganic & Medicinal Chemistry Letters. Feb 1994. 4 (3) : 509-514.