MG-262
MG-262 (Z-Leu-Leu-LeuB (OH) 2; ZL3B) is a reversible proteasome inhibitor. MG-262 down-regulates VEGF receptor Flt-1. MG-262 inhibits cell growth and induces apoptosis in malignant cells. MG-262 induces reactive oxygen species (ROS) . MG-262 can be used for anti-cancer study[1][2][3][4][5].
Product Specifications
CAS Number
179324-22-2
Product Name Alternative
Z-Leu-Leu-LeuB (OH) 2; ZL3B
UNSPSC
12352005
Target
Apoptosis; Proteasome; Reactive Oxygen Species (ROS) ; VEGFR
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/mg-262.html
Purity
95.0
Solubility
DMSO : 5 mg/mL (ultrasonic)
Smiles
O=C(N[C@H](B(O)O)CC(C)C)[C@H](CC(C)C)NC([C@H](CC(C)C)NC(OCC1=CC=CC=C1)=O)=O
Molecular Formula
C25H42BN3O6
Molecular Weight
491.43
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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