Ac-VEID-CHO (TFA)
Ac-VEID-CHO (TFA) is a peptide-derived caspase inhibitor and has potency of inhibition for Caspase-6, Caspase-3 and Caspase-7 with IC50 values of 16.2 nM, 13.6 nM and 162.1 nM, respectively. Ac-VEID-CHO (TFA) can be used for the research of neurodegenerative conditions including Alzheimer’s and Huntington’s disease[1].
Product Specifications
UNSPSC
12352209
Target
Caspase
Type
Peptides
Related Pathways
Apoptosis
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ac-veid-cho-tfa.html
Purity
99.77
Solubility
H2O : 1 mg/mL (ultrasonic; warming)
Smiles
OC(C(F)(F)F)=O.CC[C@@H]([C@@H](C(N[C@H](C=O)CC(O)=O)=O)NC([C@@H](NC([C@H](C(C)C)NC(C)=O)=O)CCC(O)=O)=O)C
Molecular Formula
C24H37F3N4O11
Molecular Weight
614.57
References & Citations
[1]Robert Mintzer, et al. A whole cell assay to measure caspase-6 activity by detecting cleavage of lamin A/C. PLoS One. 2012;7 (1) :e30376.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
Caspase 3; Caspase 6; Caspase 7
Available Sizes
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