GlcNAcstatin
GlcNAcstatin is a selective glucoimidazole-based bacterial O-GlcNAcase inhibitor with a Ki of 4.6 pM. GlcNAcstatin shows 100000-fold selectivity over HexA/B[1].
Product Specifications
CAS Number
922163-64-2
UNSPSC
12352005
Target
Bacterial; OGA
Type
Reference compound
Related Pathways
Anti-infection; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/glcnacstatin.html
Solubility
10 mM in DMSO
Smiles
CC(C)C(N[C@H]1C2=NC(CCC3=CC=CC=C3)=CN2[C@H](CO)[C@@H](O)[C@@H]1O)=O
Molecular Formula
C20H27N3O4
Molecular Weight
373.45
References & Citations
[1]Helge C Dorfmueller, et al. GlcNAcstatin: a picomolar, selective O-GlcNAcase inhibitor that modulates intracellular O-glcNAcylation levels. J Am Chem Soc. 2006 Dec 27;128 (51) :16484-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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