LY2881835
LY2881835 is a potent and selective agonist of G protein-coupled receptor 40 (GPR40) . LY2881835 has efficacious and durable dose-dependent reductions in glucose levels along with significant increases in insulin and GLP-1 secretion. LY2881835 has the potential for the research of type 2 diabetes mellitus[1]. LY2881835 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
1292290-38-0
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Free Fatty Acid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/ly2881835.html
Solubility
10 mM in DMSO
Smiles
OC(C[C@H](C#CC)C(C=C1)=CC=C1OCC(C=C2)=CC=C2CN3CCC4(CC3)C5=CC=CC=C5C=C4)=O
Molecular Formula
C33H33NO3
Molecular Weight
491.62
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
Frequently Asked Questions
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