N-Acetyl-5-hydroxytryptamine-d3
Product Specifications
UNSPSC Description
N-Acetyl-5-hydroxytryptamine-d3 is the deuterium labeled N-Acetyl-5-hydroxytryptamine. N-Acetyl-5-hydroxytryptamine is a Melatonin precursor, and that it can potently activate TrkB receptor[1][2].
Target Antigen
Endogenous Metabolite; Trk Receptor
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease;Neuronal Signaling;Protein Tyrosine Kinase/RTK
Field of Research
Neurological Disease
Purity
98.0
Solubility
10 mM in DMSO
Smiles
[2H]C([2H])([2H])C(NCCC(C1=C2)=CNC1=CC=C2O)=O
Molecular Weight
221.27
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Jang SW, et al. N-acetylserotonin activates TrkB receptor in a circadian rhythm. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3876-81.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Clinical Information
No Development Reported
CAS Number
2001098-07-1
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