Dihydroactinidiolide

Dihydroactinidiolide, existing in plant leaves and fruits, is a potent plant growth inhibitor, a regulator of gene expression and is responsible for photo acclimation in Arabidopsis. Dihydroactinidiolide has antioxidant activity, antibacterial activity, anticancer activity and neuroprotective effect[1]. Dihydroactinidiolide is also an inhibitor of AChE (IC50=34.03 nM) and has scavenging activities for DPPH and (.NO) . Dihydroactinidiolide is present in plant leaves and fruits and is a potent plant growth inhibitor, regulator of gene expression, and responsible for light adaptation in Arabidopsis.

Product Specifications

CAS Number

[17092-92-1]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H332, H335

Target

Bacterial; Cholinesterase (ChE)

Type

Natural Products

Related Pathways

Anti-infection; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/dihydroactinidiolide.html

Purity

98.10

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1O[C@@]2(C)C(C(C)(C)CCC2)=C1

Molecular Formula

C11H16O2

Molecular Weight

180.24

Precautions

H302, H315, H319, H332, H335

References & Citations

[1]Das M, et al. Dihydroactinidiolide, a natural product against Aβ25-35 induced toxicity in Neuro2a cells: Synthesis, in silico and in vitro studies. Bioorg Chem. 2018 Dec;81:340-349.|[2]Das M, et al. Dihydroactinidiolide, a natural product against Aβ25-35 induced toxicity in Neuro2a cells: Synthesis, in silico and in vitro studies. Bioorg Chem. 2018 Dec;81:340-349.