Penciclovir (sodium)
Penciclovir (VSA 671) sodium is a potent and selective anti-herpesvirus agent with EC50 values of 0.5, 0.8 μg/ml for HSV-1 (HFEM), HSV-2 (MS), respectively. Penciclovir sodium shows anti-herpesvirus activity with no-toxic. Penciclovir sodium preventes mortality in mouse[1][2].
Product Specifications
CAS Number
97845-62-0
Product Name Alternative
VSA 671 (sodium) ; BRL 39123A; BRL 39123D
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
HSV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/penciclovir-sodium.html
Solubility
10 mM in DMSO
Smiles
OCC(CO[Na])CCN1C2=C(C(NC(N)=N2)=O)N=C1
Molecular Formula
C10H14N5NaO3
Molecular Weight
275.24
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501
References & Citations
[1]M.R. Boyd, et al. Penciclovir: a review of its spectrum of activity, selectivity, and cross-resistance pattern. Antiviral Chemistry and Chemotherapy, 1993, (1) : 3-11.|[2]de la Fuente R, et al. The acyclic nucleoside analogue penciclovir is a potent inhibitor of equine herpesvirus type 1 (EHV-1) in tissue culture and in a murine model. Antiviral Res. 1992 May;18 (1) :77-89.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
HSV-1; HSV-2
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