Penciclovir (sodium)

Penciclovir (VSA 671) sodium is a potent and selective anti-herpesvirus agent with EC50 values of 0.5, 0.8 μg/ml for HSV-1 (HFEM), HSV-2 (MS), respectively. Penciclovir sodium shows anti-herpesvirus activity with no-toxic. Penciclovir sodium preventes mortality in mouse[1][2].

Product Specifications

CAS Number

[97845-62-0]

Product Name Alternative

VSA 671 (sodium) ; BRL 39123A; BRL 39123D

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

HSV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/penciclovir-sodium.html

Solubility

10 mM in DMSO

Smiles

OCC(CO[Na])CCN1C2=C(C(NC(N)=N2)=O)N=C1

Molecular Formula

C10H14N5NaO3

Molecular Weight

275.24

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501

References & Citations

[1]M.R. Boyd, et al. Penciclovir: a review of its spectrum of activity, selectivity, and cross-resistance pattern. Antiviral Chemistry and Chemotherapy, 1993, (1) : 3-11.|[2]de la Fuente R, et al. The acyclic nucleoside analogue penciclovir is a potent inhibitor of equine herpesvirus type 1 (EHV-1) in tissue culture and in a murine model. Antiviral Res. 1992 May;18 (1) :77-89.