AI-3
AI-3 is a potent ARE (antioxidant response element) activator. AI-3 increases the NQO1 at the transcript levels and protein expression levels. AI-3 has the potential for the research of oxidative stress related diseases[1].
Product Specifications
CAS Number
882288-28-0
UNSPSC
12352005
Target
Others; Quinone Reductase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ai-3.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(S(=O)(C)=O)SC(Cl)=C2CC(C)(C1)C
Molecular Formula
C11H13ClO3S2
Molecular Weight
292.80
References & Citations
[1]Wang R, et al. In vitro and in vivo characterization of a tunable dual-reactivity probe of the Nrf2-ARE pathway. ACS Chem Biol. 2013 Aug 16;8 (8) :1764-74.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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