BMS-193885 (L-Lactic acid)
BMS-193885 (L-Lactic acid) is a potent, selective, and brain-penetrant neuropeptide Y1 receptor antagonist. BMS-193885 has a Ki value of 3.3 nM for the neuropeptide Y1 receptor, competitively acts on the neuropeptide Y binding site, and can reduce food intake and body weight through central Y1 inhibition[1].
Product Specifications
CAS Number
679839-66-8
UNSPSC
12352005
Target
Neuropeptide Y Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bms-193885-l-lactic-acid.html
Solubility
10 mM in DMSO
Smiles
COC(C1=C(C)NC(C)=C(C(OC)=O)C1C2=CC(NC(NCCCN3CCC(C4=CC(OC)=CC=C4)CC3)=O)=CC=C2)=O.OC([C@@H](O)C)=O
Molecular Formula
C36H48N4O9
Molecular Weight
680.79
References & Citations
[1]Ildiko Antal-Zimanyi, et al. Pharmacological characterization and appetite suppressive properties of BMS-193885, a novel and selective neuropeptide Y (1) receptor antagonist. Eur J Pharmacol. 2008 Aug 20;590 (1-3) :224-32.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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