BIBO3304 (diTFA)
BIBO3304 (diTFA) is an orally effective and selective neuropeptide Y (NPY) Y1 receptor antagonist. BIBO3304 (diTFA) has a high affinity for both human and rat Y1 receptors, with IC50 values of 0.38 and 0.72 nM, respectively. BIBO3304 (diTFA) promotes bone-tendon healing through the Wnt/β-catenin signaling pathway[1][2][3].
Product Specifications
CAS Number
2310085-85-7
UNSPSC
12352005
Target
Neuropeptide Y Receptor; Wnt
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling; Stem Cell/Wnt
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/bibo3304-ditfa.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](C(NCC1=CC=C(CNC(N)=O)C=C1)=O)CCCNC(N)=N)C(C2=CC=CC=C2)C3=CC=CC=C3.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F
Molecular Formula
C33H37F6N7O7
Molecular Weight
757.68
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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