Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Midafotel

Midafotel (SDZ-EAA 494) is a potent and comprtitive NMDA antagonist with an ED50 value of 39 nM. Midafotel causes intense stereotyped behaviors. Midafotel shows neuroprotective effects[1][2][3].

Product Specifications

CAS Number

[117414-74-1]

Product Name Alternative

SDZ-EAA 494

UNSPSC

12352005

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/midafotel.html

Purity

99.00

Smiles

OC([C@H]1CN(CCN1)C/C=C/P(O)(O)=O)=O

Molecular Formula

C8H15N2O5P

Molecular Weight

250.19

References & Citations

[1]Lowe DA, et al. D-CPP-ene (SDZ EAA 494), a potent and competitive N-methyl-D-aspartate (NMDA) antagonist: effect on spontaneous activity and NMDA-induced depolarizations in the rat neocortical slice preparation, compared with other CPP derivatives and MK-801. Neurosci Lett. 1990 Jun 8;113 (3) :315-21.|[2]Potschka H, et al. Effects of the NMDA receptor antagonist D-CPPene on extracellular levels of dopamine and dopamine and serotonin metabolites in striatum of kindled and non-kindled rats. Eur J Pharmacol. 1999 Jun 18;374 (2) :175-87. |[3]Park CK, McCulloch J, Kang JK, Choi CR. Efficacy of D-CPPene, a competitive N-methyl-D-aspartate antagonist in focal cerebral ischemia in the rat. Neurosci Lett. 1992 Nov 23;147 (1) :41-4.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-107718/Midafotel-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-107718/Midafotel-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

Phase 3

Isoform

NMDA Receptor

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Anti-SGSM3 Antibody
A09789-2 100 µL

Anti-SGSM3 Antibody

Ask
View Details
Mouse Monoclonal ACBD7 Antibody (08) [Alexa Fluor 750]
NBP3-06599AF750 0.1 mL

Mouse Monoclonal ACBD7 Antibody (08) [Alexa Fluor 750]

Ask
View Details
Human Carbonyl reductase [NADPH] 1, CBR1; CBR; CRN ELISA KIT
E6599Hu-01 48 Well

Human Carbonyl reductase [NADPH] 1, CBR1; CBR; CRN ELISA KIT

Ask
View Details
Human Carbonyl reductase [NADPH] 1, CBR1; CBR; CRN ELISA KIT
E6599Hu-02 96 Well

Human Carbonyl reductase [NADPH] 1, CBR1; CBR; CRN ELISA KIT

Ask
View Details
Human Carbonyl reductase [NADPH] 1, CBR1; CBR; CRN ELISA KIT
E6599Hu-03 5x 96 Tests

Human Carbonyl reductase [NADPH] 1, CBR1; CBR; CRN ELISA KIT

Ask
View Details
Human Carbonyl reductase [NADPH] 1, CBR1; CBR; CRN ELISA KIT
E6599Hu-04 10x 96 Tests

Human Carbonyl reductase [NADPH] 1, CBR1; CBR; CRN ELISA KIT

Ask
View Details