PMPA (NMDA antagonist)
Product Specifications
UNSPSC Description
PMPA (NMDA antagonist) is an NMDA receptor antagonist with Ki values of 0.84, 2.74, 3.53 and 4.16 μM for NR2A, NR2B, NR2C and NR2D, respectively[1].
Target Antigen
iGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pmpa-nmda-antagonist.html
Solubility
10 mM in DMSO
Smiles
O=C(C1NCCN(CP(O)(O)=O)C1)O
Molecular Weight
224.15
References & Citations
[1]Feng B, et al. The effect of competitive antagonist chain length on NMDA receptor subunit selectivity. Neuropharmacology. 2005 Mar;48(3):354-9.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-107698/PMPA-NMDA-antagonist-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-107698/
Clinical Information
No Development Reported
CAS Number
113919-36-1
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