PMPA (NMDA antagonist)
PMPA (NMDA antagonist) is an NMDA receptor antagonist with Ki values of 0.84, 2.74, 3.53 and 4.16 μM for NR2A, NR2B, NR2C and NR2D, respectively[1].
Product Specifications
CAS Number
[113919-36-1]
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pmpa-nmda-antagonist.html
Solubility
10 mM in DMSO
Smiles
O=C(C1NCCN(CP(O)(O)=O)C1)O
Molecular Formula
C6H13N2O5P
Molecular Weight
224.15
References & Citations
[1]Feng B, et al. The effect of competitive antagonist chain length on NMDA receptor subunit selectivity. Neuropharmacology. 2005 Mar;48 (3) :354-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NMDA Receptor
Curated Selection
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