N20C (hydrochloride)
N20C hydrochloride is a selective and noncompetitive open NMDA receptor open channel blocker, with micromolar affinity, fast on-off blockade kinetics, and strong voltage dependence. Neuroprotective activity[1].
Product Specifications
CAS Number
[1177583-87-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/n20c-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
NC(CNCCC(C1=CC=CC=C1)C2=CC=CC=C2)=O.Cl
Molecular Formula
C17H21ClN2O
Molecular Weight
304.81
Precautions
H302, H315, H319, H335
References & Citations
[1]Rosa Planells-Cases, et al. A novel N-methyl-D-aspartate receptor open channel blocker with in vivo neuroprotectant activity. J Pharmacol Exp Ther. 2002 Jul;302 (1) :163-73.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature, keep dry and cool
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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