Remacemide (hydrochloride)
Remacemide hydrochloride (FPL 12924AA), a moderate inhibitor of the Na+ channel, is a weak uncompetitive NMDA receptor antagonist with IC50s of 68 μM and 76 μM for MK-801 binding and NMDA currents, respectively[1]. Remacemide hydrochloride is an anticonvulsant agent[2].
Product Specifications
CAS Number
[111686-79-4]
Product Name Alternative
FPL 12924AA
UNSPSC
12352005
Hazard Statement
H302-H318-H410
Target
IGluR; Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/remacemide-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
NCC(NC(C)(C1=CC=CC=C1)CC2=CC=CC=C2)=O.[H]Cl
Molecular Formula
C17H21ClN2O
Molecular Weight
304.81
Precautions
P264-P270-P273-P280-P305+P351+P338-P330-P391-P501
References & Citations
+
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NMDA Receptor
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