RJR-2429 (dihydrochloride)

RJR 2429 hydrochloride is a α4β2 and α7 nAChR agonist[1].

Product Specifications

CAS Number

[1021418-53-0]

UNSPSC

12352005

Target

NAChR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/rjr-2429-dihydrochloride.html

Solubility

10 mM in DMSO

Smiles

[H]Cl.[H]Cl.C1(C2=CN=CC=C2)N3CCC(CC3)C1

Molecular Formula

C12H18Cl2N2

Molecular Weight

261.19

References & Citations

[1]Bhatti BS, et al. Synthesis of 2- (pyridin-3-yl) -1-azabicyclo[3.2.2]nonane, 2- (pyridin-3-yl) -1-azabicyclo[2.2.2]octane, and 2- (pyridin-3-yl) -1-azabicyclo[3.2.1]octane, a class of potent nicotinic acetylcholine receptor-ligands. J Org Chem. 2008 May 2;73 (9) :3497-507.