Oxprenoate (potassium)
Oxprenoate potassium is a potent mineralocorticoid (MR) antagonist. Oxprenoate potassium accentuates DEX (dexamethasone) -induced apoptosis[1].
Product Specifications
CAS Number
[76676-34-1]
Product Name Alternative
RU 28318
UNSPSC
12352211
Target
Mineralocorticoid Receptor
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/oxprenoate-potassium.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
CCC[C@H](CC1=CC2=O)[C@@]([C@@](CC3)([H])[C@]1(CC2)C)([H])[C@@](CC[C@](O)4CCC(O[K])=O)([H])[C@@]43C
Molecular Formula
C25H37KO4
Molecular Weight
440.66
References & Citations
[1]Crochemore C, et al. Direct targeting of hippocampal neurons for apoptosis by glucocorticoids is reversible by mineralocorticoid receptor activation. Mol Psychiatry. 2005 Aug;10 (8) :790-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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