(E/Z) -BIX02188
(E/Z) -BIX02188 is a MEK5/ERK5 pathway inhibitor. (E/Z) -BIX02188 inhibits the catalytic function of purified MEK5 enzyme. (E/Z) -BIX02188 can be used for the role of MEK5/ERK5 pathway in various biological systems [1].
Product Specifications
CAS Number
[1094614-84-2]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/e-z-bix02188.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C2C(NC(/C2=C(C3=CC=CC=C3)\NC4=CC=CC(CN(C)C)=C4)=O)=C1)N
Molecular Formula
C25H24N4O2
Molecular Weight
412.48
Precautions
H302, H315, H319, H335
References & Citations
[1]Tatake RJ, et al. Identification of pharmacological inhibitors of the MEK5/ERK5 pathway. Biochem Biophys Res Commun. 2008 Dec 5;377 (1) :120-5.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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