BAY-u 9773
BAY-u 9773 is a non-selective antagonist of the CysLT receptors (cysteinyl leukotrienes receptors) with about the same IC50 for CysLT1 and CysLT2. BAY-u9773 is used for the inhibition of LT responses[1].
Product Specifications
CAS Number
[154978-38-8]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Leukotriene Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/bay-u-9773.html
Concentration
211.58 μM * 250 μL in Ethanol
Purity
95.5
Solubility
10 mM in DMSO
Smiles
OC(CCC[C@H](O)[C@@H](/C=C/C=C/C=C\C/C=C\CCCCC)SC1=CC=C(C=C1)C(O)=O)=O
Molecular Formula
C27H36O5S
Molecular Weight
472.64
Precautions
H302, H315, H319, H335
References & Citations
[1]Tudhope SR, et al. BAY u9773, a novel antagonist of cysteinyl-leukotrienes with activity against two receptor subtypes. Eur J Pharmacol. 1994 Nov 3;264 (3) :317-23.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C, protect from light
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
LTC4/CysLT2; LTD4/CysLT1
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