BAY-u 9773

BAY-u 9773 is a non-selective antagonist of the CysLT receptors (cysteinyl leukotrienes receptors) with about the same IC50 for CysLT1 and CysLT2. BAY-u9773 is used for the inhibition of LT responses[1].

Product Specifications

CAS Number

[154978-38-8]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Leukotriene Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/bay-u-9773.html

Concentration

211.58 μM * 250 μL in Ethanol

Purity

95.5

Solubility

10 mM in DMSO

Smiles

OC(CCC[C@H](O)[C@@H](/C=C/C=C/C=C\C/C=C\CCCCC)SC1=CC=C(C=C1)C(O)=O)=O

Molecular Formula

C27H36O5S

Molecular Weight

472.64

Precautions

H302, H315, H319, H335

References & Citations

[1]Tudhope SR, et al. BAY u9773, a novel antagonist of cysteinyl-leukotrienes with activity against two receptor subtypes. Eur J Pharmacol. 1994 Nov 3;264 (3) :317-23.