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FPL-55712 (free base)

FPL-55712 free base is a leukotriene receptor antagonist. FPL-55712 free base is also an antagonist of slow reacting substance of anaphylaxis (SRS-A) . FPL-55712 free base inhibits leukotriene-induced bronchoconstriction[1][2][3].

Product Specifications

UNSPSC

12352005

Target

Leukotriene Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/fpl-55712-free-base.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

O=C(C(OC1=C(CCC)C(OCC(COC2=CC=C(C(O)=C2CCC)C(C)=O)O)=CC=C13)=CC3=O)O

Molecular Formula

C27H30O9

Molecular Weight

498.52

References & Citations

[1]O'Donnell M, et al. Pharmacologic properties of FPL 55712 administered by aerosol. Agents Actions. 1984 Jan;14 (1) :43-8.|[2]Folkerts G, Vet al. Leukotrienes mediate tracheal hyperresponsiveness after nitric oxide synthesis inhibition. Eur J Pharmacol. 1995 Oct 16;285 (2) :R1-2.|[3]Chand N. FPL 55712 -- an antagonist of slow reacting substance of anaphylaxis (SRS-A) : a review. Agents Actions. 1979 Jun;9 (2) :133-40.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-107607/FPL-55712-free-base-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-107607/FPL-55712-free-base-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

No Development Reported

CAS Number

[40785-97-5]

Available Sizes

Curated Selection

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