FPL-55712 (free base)
FPL-55712 free base is a leukotriene receptor antagonist. FPL-55712 free base is also an antagonist of slow reacting substance of anaphylaxis (SRS-A) . FPL-55712 free base inhibits leukotriene-induced bronchoconstriction[1][2][3].
Product Specifications
CAS Number
40785-97-5
UNSPSC
12352005
Target
Leukotriene Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/fpl-55712-free-base.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
O=C(C(OC1=C(CCC)C(OCC(COC2=CC=C(C(O)=C2CCC)C(C)=O)O)=CC=C13)=CC3=O)O
Molecular Formula
C27H30O9
Molecular Weight
498.52
References & Citations
[1]O'Donnell M, et al. Pharmacologic properties of FPL 55712 administered by aerosol. Agents Actions. 1984 Jan;14 (1) :43-8.|[2]Folkerts G, Vet al. Leukotrienes mediate tracheal hyperresponsiveness after nitric oxide synthesis inhibition. Eur J Pharmacol. 1995 Oct 16;285 (2) :R1-2.|[3]Chand N. FPL 55712 -- an antagonist of slow reacting substance of anaphylaxis (SRS-A) : a review. Agents Actions. 1979 Jun;9 (2) :133-40.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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