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HDAC6-IN-7

TCS HDAC6 20b is a HDAC6-selective inhibitor. TCS HDAC6 20b blocks the growth of estrogen receptor α-positive breast cancer MCF-7 cells[1].

Product Specifications

CAS Number

956154-63-5

UNSPSC

12352211

Hazard Statement

H225-H319

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hdac6-in-7.html

Solubility

10 mM in DMSO

Smiles

CC(C)(C)OC(N[C@@H](CCCCCSC(C(C)C)=O)C(NC12C[C@H](C3)C[C@H](C[C@H]3C2)C1)=O)=O

Molecular Formula

C26H44N2O4S

Molecular Weight

480.70

Precautions

P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P370+P378-P403+P235-P501

References & Citations

[1]Yukihiro Itoh, et al. Design, synthesis, structure--selectivity relationship, and effect on human cancer cells of a novel series of histone deacetylase 6-selective inhibitors. J Med Chem. 2007 Nov 1;50 (22) :5425-38.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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