HDAC6-IN-7
TCS HDAC6 20b is a HDAC6-selective inhibitor. TCS HDAC6 20b blocks the growth of estrogen receptor α-positive breast cancer MCF-7 cells[1].
Product Specifications
CAS Number
[956154-63-5]
UNSPSC
12352211
Hazard Statement
H225-H319
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hdac6-in-7.html
Solubility
10 mM in DMSO
Smiles
CC(C)(C)OC(N[C@@H](CCCCCSC(C(C)C)=O)C(NC12C[C@H](C3)C[C@H](C[C@H]3C2)C1)=O)=O
Molecular Formula
C26H44N2O4S
Molecular Weight
480.70
Precautions
P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P370+P378-P403+P235-P501
References & Citations
[1]Yukihiro Itoh, et al. Design, synthesis, structure--selectivity relationship, and effect on human cancer cells of a novel series of histone deacetylase 6-selective inhibitors. J Med Chem. 2007 Nov 1;50 (22) :5425-38.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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