8-pCPT-2'-O-Me-cAMP-AM
8-pCPT-2'-O-Me-cAMP-AM is a cyclic AMP analogue, selectively activates Epac-Rap signaling pathway. 8-pCPT-2'-O-Me-cAMP-AM protects renal function by activating Epac from ischemia injury. 8-pCPT-2'-O-Me-cAMP-AM also stimulates insulin secretion by interaction with PKA pathway[1][2].
Product Specifications
UNSPSC
12352005
Target
PKA
Type
Reference compound
Related Pathways
Stem Cell/Wnt; TGF-beta/Smad
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/8-pcpt-2-o-me-camp-am.html
Purity
99.0
Solubility
DMSO : 55.79 mg/mL (ultrasonic)
Smiles
NC1=C2C(N([C@@]3([H])[C@@H]([C@@]4([H])[C@](COP(OCOC(C)=O)(O4)=O)([H])O3)OC)C(SC5=CC=C(C=C5)Cl)=N2)=NC=N1
Molecular Formula
C20H21ClN5O8PS
Molecular Weight
557.90
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-107544/8-pCPT-2-O-Me-cAMP-AM-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-107544/8-pCPT-2-O-Me-cAMP-AM-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
No Development Reported
CAS Number
[1152197-23-3]
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