Oleoylethanolamide-d4

Oleoylethanolamide-d4 is the deuterium labeled Oleoylethanolamide. Oleoylethanolamide is a high affinity endogenous PPAR-α agonist, which plays an important role in the treatment of obesity and arteriosclerosis.

Product Specifications

CAS Number

[946524-36-3]

Product Name Alternative

N-Oleoylethanolamide-d4; Oleamide MEA-d4; Oleic acid monoethanolamide-d4

UNSPSC

12352211

Hazard Statement

H225, H319

Target

Endogenous Metabolite; Isotope-Labeled Compounds; PPAR

Type

Isotope-Labeled Compounds

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor

Field of Research

Metabolic Disease; Cardiovascular Disease

Concentration

3.03 mM * 1 mL in Ethanol

Purity

99.90

Solubility

DMSO : 20.83 mg/mL (ultrasonic; warming)

Smiles

CCCCCCCC/C=C\CCCCCCCC(NC([2H])([2H])C([2H])([2H])O)=O

Molecular Formula

C20H35D4NO2

Molecular Weight

329.55

Precautions

H225, H319

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Chen L, et al. Oleoylethanolamide, an endogenous PPAR-α ligand, attenuates liver fibrosis targeting hepatic stellate cells. Oncotarget. 2015 Dec 15;6 (40) :42530-40